Living versus deceased donor kidneys (LD kidneys last longer...) - Hallo friend American jobs and vicinity, In the article you read this time with the title Living versus deceased donor kidneys (LD kidneys last longer...), we have prepared well for this article you read and download the information therein. hopefully fill posts Article bank, Article contracting, Article general, Article health, Article manufacturing, Article marketing, Article teachers, Article telecommunications, Article The latest, we write this you can understand. Well, happy reading.

Title : Living versus deceased donor kidneys (LD kidneys last longer...)
link : Living versus deceased donor kidneys (LD kidneys last longer...)

Living versus deceased donor kidneys (LD kidneys last longer...)

It appears that even a not so well matched living donor kidney lasts longer than a deceased donor kidney...

Living Donation Has a Greater Impact on Renal Allograft Survival Than HLA Matching in Pediatric Renal Transplant Recipients
Marlais, Matko MRCPCH; Hudson, Alex MSc; Pankhurst, Laura MSc; Fuggle, Susan V. D.Phil.; Marks, Stephen D. MD
TRANSPLANTATION, Dec. 2016 Volume: 100  Issue: 12  Pages: 2717-2722

Background: Living donor (LD) kidney transplantation accounts for around half of all pediatric renal transplant recipients and results in improved renal allograft survival. The aim of this study was to determine the effect of HLA matching on deceased and LD renal allograft outcomes in pediatric recipients.

Methods: Data were obtained from the UK Transplant Registry held by NHS Blood and Transplant on all children who received a donation after brain death (DBD) or LD kidney-only transplant between 2000 and 2011. HLA-A, HLA-B and HLA-DR mismatches were categorized into 4 levels and 2 groups. Data were fully anonymized.

Results: One thousand three hundred seventy-eight pediatric renal transplant recipients were analyzed; 804 (58%) received a DBD donor kidney, 574 (42%) received an LD kidney. Five-year renal allograft survival was superior for children receiving a poorly HLA-matched LD kidney transplant (88%, 95% confidence interval [95% CI], 84-91%) compared with children receiving a well HLA-matched DBD kidney transplant (83%, 95% CI, 80-86%, log rank test P = 0.03). Five-year renal allograft survival was superior for children receiving an LD kidney with 1 or 2 HLA-DR mismatches (88%, 95% CI, 84-91%) compared with children receiving a DBD kidney with 0 HLA-DR mismatches (83%, 95% CI, 80-86%, log rank test P = 0.03).

Conclusions: In children, poorly HLA-matched LD renal transplant outcomes are not inferior when compared with well HLA-matched DBD renal transplants. It is difficult to justify preferentially waiting for an improved HLA-matched DBD kidney when a poorer HLA-matched LD kidney transplant is available.

Thus Article Living versus deceased donor kidneys (LD kidneys last longer...)

that is all articles Living versus deceased donor kidneys (LD kidneys last longer...) This time, hopefully can provide benefits to all of you. Okay, see you in another article post.

You now read the article Living versus deceased donor kidneys (LD kidneys last longer...) with the link address https://americanjobsandvicinity.blogspot.com/2017/05/living-versus-deceased-donor-kidneys-ld.html

Tweet

Subscribe to receive free email updates: